Everything about Microspheres
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  • Fluorochromes – Excitation and Emission Wavelengths

    Below is a very useful table of various Fluorochromes that can be used in research requiring precise responses.  For more information about Fluorescent Microspheres that utilize fluorochromes check out this related article. “Fluorescent Microspheres – Properties and Applications

    The fluorochrome table is also available for download as a pdf.

    Table of Excitation and Emission WavelengthsFLUOROCHROME EXCITATION(nm)
    EMISSION (nm)
    3-Hydroxypyrene 5,8,10-Tri Sulfonic acid 403 513
    5-Hydroxy Tryptamine 380-415 520-530
    5-Hydroxy Tryptamine (5-HT) 400 530
    Acid Fuchsin 540 630
    Acridine Orange (bound to DNA) 502 526
    Acridine Red 455-600 560-680
    Acridine Yellow 470 550
    Acriflavin 436 520
    AFA (Acriflavin Feulgen SITSA) 355-425 460
    Alizarin Complexon 530-560 580
    Alizarin Red 530-560 580
    Allophycocyanin 650 661
    ACMA 430 474
    Aminoactinomycin D 555 655
    Aminocoumarin 350 445
    Anthroyl Stearate 361-381 446
    Astrazon Brilliant Red 4G 500 585
    Astrazon Orange R 470 540
    Astrazon Red 6B 520 595
    Astrazon Yellow 7 GLL 450 480
    Atabrine 436 490
    Auramine 460 550
    Aurophosphine 450-490 515
    Aurophosphine G Continue reading “Fluorochromes – Excitation and Emission Wavelengths” »
  • Solid Polyethylene Microspheres for Effects in Color Cosmetics

    A recent article in Cosmetics & Toiletries magazine describes the use Solid Polyethylene Mirospheres for Effects in Color Cosmetics.

    Flesh Tone Microspheres - Color Matched to Skin Sample

    Flesh Tone Microspheres - Color Matched to Skin Sample

    Micropsheres have been used in cosmetics for some time, primarily as fillers and exfoliators. Most recently scientists started to utilize light reflecting properties of microspheres for creating unique optical effects, such as optical blurring and wrinkle filling.  Due to light scattering effects of the spherical surface, formulating with appropriate microspheres can minimize the appearance of fine lines and uneven skin tone, due to optically reducing contrast on the skin.

    The spherical shape and smooth surface of microspheres creates a low friction ball-bearing effect that gives formulations an elegant, silky feel. This ball-bearing effect promotes better blending on the skin and a more natural finish due to the enhanced slip, glide and omnidirectional spreadability, imparting a cream to powder texture. Outstanding roundness also provides lubrication during application, which enhances the tactile experience of a cosmetic product. Continue reading “Solid Polyethylene Microspheres for Effects in Color Cosmetics” »

  • Cosmetic Applications of Injectable Polymer Microspheres

    Polymer microspheres, in particular injectable polymer particles with a diameter in the range of 30−300 μm, are becoming widely used as a biomaterial in different clinical fields, such as cosmetic surgery, reconstructive surgery, and urology.  Injectable skin fillers offer many benefits in cosmetic dermatology, allowing new forms of facial rejuvenation and wrinkle treatment without surgery. Injectable skin and wrinkle fillers are used to increase tissue volume, reduce wrinkles, and improve skin’s overall contour.

    According to The American Society for Aesthetic Plastic Surgery,  two formulations of fillers that are based on microsphere technology are FDA approved for use, differing in design and expected longevity of results.  These injectable microspheres products are used for volume replacement and for deep facial wrinkles (such as the nasolabial folds.) They are not approved for use in the lips.

    One of cosmetic dermatology products using injectable microspheres is ArteFill® – a new breed of dermal filler that offers longer lasting results than other cosmetic filler injections. ArteFill® (known as Artecoll® outside of the United States) is made of polymethylmethacrylate (PMMA) microspheres (miniature beads) that are suspended in bovine collagen. Tiny microspheres are made of non-resorbable polymethylmethacrylate – a biocompatable compound that has been used for years.  PMMA has been used since the early 1930s in such common procedures as dental prostheses, eye lenses, bone repair, orthopedics and in pacemakers.  PMMA microspheres are well tolerated by human tissue (no rejection). Continue reading “Cosmetic Applications of Injectable Polymer Microspheres” »