Everything about Microspheres
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  • Fluorescent Microspheres Used for Experiments in Plant Canopies

    Fluorescent Microspheres - Polymer Spheres - 1g/cc

    Fluorescent Microspheres – Polymer Spheres – 1g/cc

    The University of Utah in collaboration with USDA Labs in Corvallis, OR performed five field campaigns in commercial vineyards in Oregon’s Willamette Valley.  Among the methodologies developed over the five-years experiment was the use of fluorescent microsheres as a fungal spore analog.  The microspheres used were inert fluorescing polyethylene micropsheres in four separate colors manufactured by Cospheric.

    The article attached below outlines the technology developed as well as microspheres sampling and meteorological equipment used in the experiments.  The authors of the article conclude that “these techniques have enabled for incredibly detailed research into particle plume dynamics in a vineyard.”

    NMiller_Poster_Methods

     

     

  • Microspheres Used as a Drug Delivery System

    There has been numerous studies done and articles published in scientific publications about the advantages of microspheres as a drug delivery system vs conventional approach to drug delivery.  Design, Development and Future Application of Microspheres by Divya Rawat , U.K> Singh and Faizi Muzaffar,  Kharvel Subharti College of Pharmacy, published in PharmaTutor discusses the types of microspheres that posses the properties needed for various drug delivery systems, their advantages and limitations.  The micropsheres best suitable to be used in biomedical applications, research and lab experiments are polystyrene.  According to the article: “Polystyrene microspheres are typically used in biomedical applications due to their ability to facilitate procedures such as cell sorting and immune precipitation. Proteins and ligands adsorb onto polystyrene readily and permanently, which makes polystyrene microspheres suitable for medical research and biological laboratory experiments. Polyethylene microspheres are commonly used as permanent or temporary filler. Lower melting temperature enables polyethylene microspheres to create porous structures in ceramics and other materials. High sphericity of polyethylene microspheres, as well as availability of colored and fluorescent microspheres, makes them highly desirable for flow visualization and fluid flow analysis, microscopy techniques, health sciences, process troubleshooting and numerous research applications.”

    Another research paper that discusses advantages and disadvantages of microspheres use for drug delivery, as well as techniques to prepare microsheres and principle behind drug delivery system is Microspheres as Drug Carriers for Controlled Drug Delivery: a Review by Nisha Sharma, Neha Purwar and Prakash Chandra Gupta, University Institute of Pharmacy, C.S.J.M. University, Kanpur, India published in International Journal of Pharmaceutical Sciences and Research.  Polymer microspheres were used for the experiment. The authors conclude that “microspheres are better choice of drug delivery system than many other types of drug delivery system. In future by combining various other strategies, microspheres will find the central and significant place in novel drug delivery, particularly in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted, specific and effective in-vitro delivery and supplements as miniature version of diseased organ and tissues in the body.”

  • Use of Polyethylene Spheres for Analyzing Microplastic Transport in Correlation with Earthworm Presence

    Work by Matthias C. Rillig, Lisa Ziersch, and Stefan Hempel at Freie Universität and Brandenburg Institute of Advanced Biodiversity Research in Berlin has been published in an article titled Microplastic transport in soil by earthworms. This article investigates earthworms effect on microplastic movement into subsurface soil layers.

    Polyethylene Microplastic

    With the increase in plastic usage in recent decades the issue of how this discarded plastic will affect marine environments has been studied extensively. However, effects of microplastics on soil environments have not been tested to the same extent. Scientists have begun testing microplastic movement into lower soil layers by analyzing how differing sized polyethylene beads moved in a 21-day period with and without earthworm facilitation.

    The experiment was designed to confirm the assumption that earthworms would aid in particle movement. Results found earthworms to have a significant positive effect on transporting polyethylene particles from the soil surface. While particle size was also an important factor on the level of transportation into subsurface environments. With polyethylene spheres in the size range 710-850um being significantly more likely to move into the lowest layer when earthworms were present.

    With this experiment showing the ability of earthworms to transport microplastics into subsurface layers more research needs to be done to determine the effects this may have on the soil environment and the worms themselves. Including the multitude of other organisms that could also facilitate similar transportation. As well as the possibilities of microplastics reaching ground water where problems similar to those realized in marine systems could occur.

  • Neutrally Buoyant in Water – Microspheres with Specific Gravity of 1g/cc

    Cospheric offers polymer microspheres with specific gravity of 1g/cc are specifically designed to match the density of water for optimal suspension of particles. Suspension of microspheres in water enables the visualization and characterization of fluid flow and testing the capability of devices to withstand particulate matter in the fluid stream, ensuring that microspheres do not settle and do not float on the surface.  Most of these polymer microspheres are at least moderately opaque and clearly visible in water, clear or translucent liquids.

    Many Colors are available in sizes from 10um up to 1180um,  of polyethylene microspheres are available with specific density of 1g/cc, designed for optimum suspension in water for fluid flow visualization.  Colors include Violet, Orange, Yellow, Fluorescent, Grey, Pink, Blue, and many fluorescent colors.

    600-710um violet PE microspheres250-300um ORANGE PE Microspheresblue microspheres 355-425um Yellow microspheresGrey Microspheres PE

  • Phosphorescent Microspheres – Long Afterglow Particles

    Phosphorecent Beads - Yellow Green Afterglow Spheres

    Phosphorecent Beads - Yellow Green Afterglow

    Phosphorescent microspheres in particle sizes 10 to 600 microns are now available from Cospheric LLC. These phosphorescent particles are 90% spherical and appear to be off-white under ordinary daylight or regular room illumination.  However, when the lights are turned off these phosphorescent particles exhibit phosphorescent yellow-green after-glow.

    The spheres have tight particle size distributions and are > 90% within size range.  Polymer spheres that incorporate proprietary phosphorescent ingredient have a melting point of 115°C , and are mechanically stable past 90°C.  Phosphorescent beads are also inert in most solvents.

    Phosphorescent Decay CurveIntensity of Phosphorescent Afterglow:

    Intensity according to DIN 67510-1

    800 mcd/m2 at 1 minute
    180 mcd/m2 at 5 minutes
    90 mcd/m2 at 10 minutes
    12 mcd/m2 at 1 hour
    5 mcd/m2 at 2 hours

    Excitation and Phosphorescent Emission Curve:
    Excitation and Emission Spectra