Everything about Microspheres
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  • Reflective Billboard – Creative Outdoor Billboard for McDonald’s

    What a creative alternative to power-hungry digital displays. This large outdoor billboard is totally environmentally friendly because compared to LCD and LED displays that run on electricity, this display takes no energy to run. This creative outdoor billboard is made with reflective tape, visible only when illuminated by headlights in the darkness, created by ad agency Cossette.  To promote a local 24-hour McDonald’s in Canada, Cossette Vancouver designed this reflective billboard that’s only visible at night when cars pass by. By day, the billboard appears blank with no message, but at night, motorists driving along the highway reveal Mickey-D’s clever advertisement with their car headlights. Not only does this display save energy, it can be put anywhere, even in cities with strict requirements on flashing and lit displays.

    Even though this particular display was made using reflective tape, many types of retroreflective media can be made by incorporating retroreflective microspheres in a variety of substances. Retroreflective Microspheres are made by applying a half-shell aluminum coating on solid barium titanate glass microspheres. The spheres hemispherically coated with a thin aluminum shell produce a bright retroreflective response directed back to the light source.

  • Black Paramagnetic Spheres and Micropsheres 10micron to 1.4mm

    Black polyethylene paramagnetic microspheres are now available in wide selection of particle sizes ranging from 10 micron to 1.4 millimeters. The particles are supplied in dry powder form. No solvents are used in the manufacturing process. Black paramagnetic polymer microspheres have a strong response to magnetic fields and can be manipulated with a magnet. Highly opaque particles with maximum hiding power.

    Paramagnetic microspheres have the ability to increase in magnetization with an applied magnetic field and loose their magnetism when the field is removed. Neither hysteresis nor residual magnetization is observed and that provides the end use two very practical advantages:

    • When the filed is removed, the microspheres demagnetize and re-disperse easily. This property allows efficient washing steps, low background and good reproducibility.
    • The behavior of the microspheres is always the same whatever the magnetization cycles may be. Such behavior is a key point for automated instrument.

    According to Wikipedia, paramagnetic materials have a small, positive susceptibility to magnetic fields. These materials are slightly attracted by a magnetic field and the material does not retain the magnetic properties when the external field is removed. Paramagnetic properties are due to the presence of some unpaired electrons, and from the realignment of the electron paths caused by the external magnetic field.

    Encyclopedia Britanica defines paramagnetism as a kind of magnetism characteristic of materials weakly attracted by a strong magnet, named and extensively investigated by the British scientist Michael Faraday beginning in 1845. Most elements and some compounds are paramagnetic. Strong paramagnetism (not to be confused with the ferromagnetism of the elements iron, cobalt, nickel, and other alloys) is exhibited by compounds containing iron, palladium, platinum, and the rare-earth elements.

    Paramagnetic microparticles are used in numerous applications where they can be manipulated with a magnet, observed and cleaned-up for reuse.

    • Solid Phase Immunoassays
    • Bacteria Detection
    • High Throughput screening
    • Rapid Tests
    • Cell Sorting
    • Biosensors
    • Nucleic Acids Technology
    • Microfluidics
  • Density Marker Beads Kit Now Available from Cospheric LLC

    Santa Barbara, CA, December 6, 2013 – Cospheric LLC, a microsphere manufacturing and distributing company, expanded their line of density marker beads which now offers six different densities including 1.02 g/cc (fluorescent green), 1.04g/cc (fluorescent orange), 1.06g/cc (fluorescent violet), 1.08 g/cc (dark blue), 1.09 g/cc (fluorescent red), and 1.13g/cc (fluorescent blue). Cospheric Density Marker Beads are now provided at a 20% concentration in an aqueous solution in 2.5ml vials, which makes the spheres easier to work with for the customers. Microspheres of different densities can be purchased individually or as a density marker beads kit.

    Microspheres of accurately known mass density are generally used as an external marker to facilitate the monitoring of the density gradient shape and range. Density marker beads enable excellent stratification and bright coloration for high visibility with the unaided eye. Historically density calibration beads in the size ranges of 212-250um or 250-300um are used. Unlike the discontinued density marker kits which used to be manufactured by GE Healthcare and sold by Sigma-Aldrich, Cospheric’s DMB density marker beads are ready for use right out of the vial, don’t need to be swollen, do not expire, and do not change density over time. Cospheric’s DMB microspheres will create Percoll gradients but will also work with any other centrifugation media. The colored microbeads may be recovered and stored for future use.

    The density marker beads provide a rapid, simple, and accurate method for measuring the density. Generally a set of several such beads, covering a range of densities, is used. In the biomedical industry researchers are sometimes looking for cells having targeted specific gravities. In order to locate these cells in test tubes it is useful to have colored marker beads which will show where the delineation between specific densities occurs. Density marker beads are also used for calibrating particles in other industries, such as agriculture, microbiology and others.

    About Cospheric LLC:
    Cospheric LLC develops, manufactures, and distributes high-quality microspheres in sizes from 10 micron to 1000 micron (1mm). Cospheric specializes in polyethylene microspheres and carries a large stock of polyethylene microspheres in many colors, fluorescent, phosphorescent, neutrally-buoyant, and paramagnetic properties. Cospheric also offers a selection of soda-lime and borosilicate glass, silica, metal-coated, and titanium dioxide-coated spheres, some available in spacer grades with very tight particle size distributions. Cospheric LLC welcomes inquiries for custom manufacturing of microspheres tuned to each customer’s unique specifications. Cospheric is an eco-friendly company that uses only recyclable materials and no solvents in the manufacturing process. For more information, pricing and sample requests visit www.cospheric.com.

    About Microspheres:
    Microspheres or beads are spherical particles usually between 1 to 1000 microns in diameter and are manufactured for wide variety of uses in research, medicine, consumer goods, paints and coatings, adhesives, personal care, household products, cosmetics, skin care, and other industries.

  • Bichromal Janus Particles, Microspheres, Microbeads – Stock selection or Custom-made

    Bichromal (half-white half-black or any other color) Microspheres, Janus Particles

    Bichromal (half-white half-black or any other color) Microspheres, Janus Particles. In this picture - Paramagnetic black microspheres with partial white coating - Magnification 40x.

    Cospheric offers unique capability to manufacture Janus microspheres and microparticles with partial coatings and dual functionality. Currently half-shell or hemispherical coatings can be applied to any sphere (glass, polymer, ceramic) in sizes 45micron in diameter and higher. Coatings can be customized for any color and coverage of between 20% to 60% of the sphere. Each coating is custom formulated for color, charge, magnetic, electric, and surface properties, and solvent resistance per customers’ needs.

    Half-coated glass microspheres - Partial coating on glass particles

    Half-coated glass microspheres - Partial coating on glass particles. In this picture - Soda lime glass microspheres with partial red coating - Magnification 40x.

    Hemispherical coatings of less than 1 micron with tolerances as low as 0.25 micron have been routinely demonstrated.  Color combinations are truly unlimited. White, black, silver, blue, green, red, yellow, brown, purple as well as transparent microspheres have been made. Sphericity of greater than 90% and custom particle size ranges are offered.

    We have successfully coated solid and hollow glass microsphere, including soda-lime, borosilicate, and barium titanate glass microspheres. We have also coated on silver.

    Half-coated Microspheres

    Half-coated Microspheres

    Optically anisotropic spheres and janus particles with magnetic half-shells have been originally developed for applications in electronic displays, such as e-paper, but are now widely used in numerous applications in diagnostics, medical research, microscopy and biotechnology, as well as electronics, due to their ability to orient themselves in response to electromagnetic field and show a visual response. This is achieved by making spheres both bipolar and bichromal, with dipole precisely aligned with two differently colored hemispheres. As the spheres align themselves, the viewer will observe the color of one hemisphere, while the other hemisphere will be hidden from view, providing an obvious strong visible indication of the presence of the field or other stimuli.  In alternating electromagnetic field, these microspheres have been proven to spin at hundreds of times per second.

  • Market Research Report – Microspheres: Technologies and Global Markets – 2013


    In summer of 2013 BCC Research has issued an updated market research report on Microspheres: Technologies and Global Markets. According to the report, the global market for microspheres was estimated to total nearly $2.2 billion in 2012 and is projected to increase to $2.4 billion in 2013; the market should total $4.4 billion by 2018 and have a five-year compound annual growth rate (CAGR) for of 12.6%.

    This report provides:

    • An overview of the global market and technologies for microspheres, which are spherical microparticles used as components in many advanced materials and composites, in the healthcare and personal care industries, and in many specialty research and development applications.
    • Analyses of global market trends, with data from 2012, estimates for 2013, and projections of compound annual growth rates (CAGRs) through 2018.
    • Identification of a variety of types of microspheres available on the market, as well as relevant industries, technologies and applications.
    • Examination of demand for microspheres in six major industries: composites, paints and coatings, oil and gas, cosmetics and personal care, biotechnology and life sciences, and medicine and medical devices.
    • Descriptions of different types of microspheres with respect to their chemical composition, including glass, ceramic, and polymer microspheres, and unique material properties that make them suitable for specific industries and applications.

    ($ MILLIONS)
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    BCC analyzes the global market for microspheres from both the manufacturing and demand points of view. Since there are several types of microspheres that vary drastically in quality, chemical properties, functionality and price, each type of microsphere is discussed in detail, including materials, manufacturing processes, advantages, prices and primary applications. Similarly, due to these variations microsphere use in six major industries are discussed and analyzed in detail.

    Detailed analysis and market forecasts are provided per industry, type of microsphere and geographic region through 2018. The report describes major players in the industry and examines recent advances in technology, newly evolving markets and companies as well other factors influencing supply and demand.

    This report analyzes microspheres—homogeneous microparticles of 1 micron to 1,000 microns in diameter. Microspheres can be solid or hollow and made from a variety of raw materials.


    BEWARE of rip-off reports that have been published this year by Research and Markets, Transparency Market Research, and other non-USA-based research firms, they contain partially plagiarized (reworded) and some completely inaccurate information.

    This authentic and accurate report was published by BCC research – a leading market research company specializing in reporting on changes driven by science and technology.  The analyst for this report is an expert in the field of microspheres. Yelena Lipovetskaya, CTO of Cospheric LLC, has more than 15 years of experience taking new technologies from concept to production in a variety of industries, including rotating microspheres electronic paper, charged microparticles for printing toner, digital displays, optical fiber, and medical devices.

    Yelena is the author of numerous applications, patents and published articles on microspheres technology and its applications and has held technical and managerial positions at Xerox Corp, Corning Inc., Cardinal Health, Gyricon, and Cbrite Inc. Yelena has a Bachelor’s degree in Chemical Engineering from Polytechnic University and a Master’s degree in Materials Science and Engineering from Rochester Institute of Technology, both in New York.