Everything about microspheres and research utilizing precision spherical particles.

Measurement Techniques for Electrostatic Charged Microspheres

Charged Microspheres Measurement TechniquesElectrostatic charge (also known as triboelectric charge) on microparticles and microspheres have been of interest to scientists in chemical, pharmaceutical, cosmetic, drug delivery, displays and other industries for many years. Until recently there were no reliable techniques to measure or quantify electrostatic charge on microparticles, with too many uncontrolled variables the measurements were inconsistent. As a result scientists were treating charging as a black box process, performing the experiments blindly as trial and error. With recent advances in microsphere manufacturing, techniques have been developed that promise not only to quantify the charge on microspheres, but control it in the manufacturing process.

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Electrostatic-based DNA Microarray Offers Medical Diagnostics Capabilities

The uses for microspheres continue to grow, a recent article published by UC-Berkley shows how DNA sequencing can be achieved through the use of statically charged microspheres. ? The key breakthrough is that they have been able to achieve a visible result through using the electrostatic repulsion of the microspheres. ? A copy of their announcement follows:

Groves,? and members of his research group Nathan Clack and Khalid Salaita, have published a paper on their technique in the journal Nature Biotechnology, which is now available online. The paper is entitled “Electrostatic readout of DNA microarrays with charged microspheres.

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