Monodisperse Silica Nanospheres and Microspheres – Dry Powder

Silica nanoparticles and nanospheres are now available in distributions of less than 10% CV in the sizes of 0.25 micron, 0.5micron, 0.75 micron, 1.0 micron, 4 micron and 8 micron.

Microspheres as Bond Line Spacers in Epoxies

Microspheres as Bond Line Spacer

Spacer Grade Glass Microspheres are presently used in gas plasma displays, automotive mirrors, electronic displays, flip chip technology, filters, sporting goods equipment, calibration standards and transformer manufacturing. Every day engineers are finding new and innovative uses for bond line spacers.

Phosphorescent Microspheres – Long Afterglow Particles

Phosphorescent microspheres in particle sizes 10 to 600 microns are now available from Cospheric LLC. These phosphorescent particles are 90% spherical and appear to be off-white under ordinary daylight or regular room illumination.? However, when the lights are turned off these phosphorescent particles exhibit phosphorescent yellow-green after-glow. The spheres have tight particle size distributions and … Read more

Microspheres in Medical Devices – MDDI Magazine

What are Microspheres?

The Microsphere of Influence

Published on MDDI Magazine
By: Yelena Lipovetskaya

Why Use Microspheres in Medical Devices?

Properties of Microspheres - Composition
Microspheres in Medical Devices

Microspheres are round microparticles that typically range from 1 to 1000 micron in diameter. Benefits of microspheres in medical devices, pharmaceuticals, and cosmetics are well known due to the microspheres’ ability to encapsulate and deliver active materials. However, there are many other lesser known advantages and functionalities of using micropsheres in medical device design, quality control, manufacturing, and testing.

The typical manufacturing process involves the microencapsulation of a drug or an active cosmetic ingredient to protect it from the deteriorating effects of the environment or for optimal release and performance in the final product. Active ingredients are released by dissolution of the capsule walls, mechanical rupture (rubbing, pressure, or impact), melting, or digestion processes. The resulting particles are often called microcapsules, which are different from solid, non-deformable microspheres.

Solid microspheres are widely used as fillers and spacers in a variety of industries. Microspheres that are used to manufacture and test medical devices are typically solid particles that are made from robust and stable raw materials such as polymers, glass, and in some cases, ceramics. Different types and grades of microspheres are available and selected based on specific application requirements.

Solid microspheres in medical devices are often used as tracers and challenge particles. In these situations, it is beneficial to use larger microspheres with sphere diameters greater than 50 micron that are vividly colored (red, blue, black, yellow, or green), since they provide contrast with the background material and visibility to the naked eye in daylight.

Colored microspheres are typically used in the testing of filtration media and systems, vial and container cleaning evaluations, flow tracing and fluid mechanics, centrifugation and sedimentation processes, pharmaceutical manufacturing, and contamination control.

Fluorescent microspheres are recommended for applications that require the use of particles that emit distinctive colors when illuminated by UV light and offer additional sensitivity for observation through the use of microscopes, lasers, and other analytical methods. Examples include microcirculation and biological research, imaging, and flow cytometry. Fluorescent microspheres can be excited and detected by a wide range of methods and are useful as experimental particles for acoustical and optical analytical systems.

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Monodisperse – Spacer Grade Microspheres

Scientists are constantly looking for narrower particle size distributions (monodispersed) of microspheres to help increase the consistency and correlation between theoretical models and verification experiments.? In an effort to fill the increasing demand for these particles Cospheric has launched a new line of spacer grade microspheres. Monodisperse microspheres are currently offered in diameters of:?? 21-24um, … Read more