One of the microsphere topics that seems to be growing these days is biodegradability.? For those of you who are unfamiliar with the topic an excellent introductory article can be found in: Advance Drug Delivery Reviews 52 (2001) 5-16, called “Biodegradable microspheres for vitreoretinal drug delivery.”? The article does a good job describing the advantages of the various polymers available, such as poly(lactic acid) [PLA], poly(glycolic acid) [PGA], and its copolymer poly(lactic-coglycolic) acid [PLGA].
The article also recommends the prefered sterlization method for drug delivery (the authors recommend irradiation).
