Cospheric Microspheres Experts

The articles on this site are written by microsphere experts from Cospheric LLC – the leading global supplier and manufacturer of precision spherical particles. When presenting information we look at a wide variety of sources, putting a big emphasis on any peer-reviewed technical articles that are getting published in reputable journals. Our goal is to present you with a well-rounded and informed view on the microsphere market, technologies, and applications. As always, our technical support staff is available via email to answer any questions, offer product recommendations, provide quotes, or address custom manufacturing inquiries. We have over 2000 microsphere products in stock. If you are not finding what you are looking for on Cospheric website, let us know! We most likely will be able to recommend an alternative product to meet your needs.

Technical Properties of PMMA Microspheres

October 15, 2021June 15, 2010 by Cospheric Microspheres Experts

PMMA Microspheres - Technical Specifications

In this article we will discuss the applications and technical properties of PMMA microspheres. What are PMMA Microspheres? PMMA micropsheres are also known as Poly(methyl methacrylate) or acrylic microspheres. PMMA, an ester of methacrylic acid (CH2=C[CH3]CO2H), is a synthetic resin produced from the polymerization of methyl methacrylate. Ever since PMMA resin was discovered and first … Read more

Solid Red Polyethylene Microspheres Announced

September 10, 2012May 28, 2010 by Cospheric Microspheres Experts

Cospheric LLC is now offering a product line of solid red polyethylene microspheres in particle size ranges from 10um to 1000um (1mm).

Fluorochromes – Excitation and Emission Wavelengths Reference Table

January 3, 2021April 28, 2010 by Cospheric Microspheres Experts

Below is a useful reference table of various Fluorochromes that can be used in research requiring precise responses. For more information about Fluorescent Microspheres that utilize fluorochromes please refer to the related article titled “Fluorescent Microspheres – Properties and Applications.”

The fluorochrome table is also available for download as a pdf.

Table of Excitation and Emission Wavelengths

FLUOROCHROME	EXCITATION(nm)	EMISSION (nm)
3-Hydroxypyrene 5,8,10-Tri Sulfonic acid	403	513
5-Hydroxy Tryptamine	380-415	520-530
5-Hydroxy Tryptamine (5-HT)	400	530
Acid Fuchsin	540	630
Acridine Orange (bound to DNA)	502	526
Acridine Red	455-600	560-680
Acridine Yellow	470	550
Acriflavin	436	520
AFA (Acriflavin Feulgen SITSA)	355-425	460
Alizarin Complexon	530-560	580
Alizarin Red	530-560	580
Allophycocyanin	650	661
ACMA	430	474
Aminoactinomycin D	555	655
Aminocoumarin	350	445
Anthroyl Stearate	361-381	446
Astrazon Brilliant Red 4G	500	585
Astrazon Orange R	470	540
Astrazon Red 6B	520	595
Astrazon Yellow 7 GLL	450	480
Atabrine	436	490
Auramine	460	550
Aurophosphine	450-490	515
Aurophosphine G Read more

Microspheres in Cosmetics – Solid Polymer Microspheres for Color Effects

January 3, 2021April 16, 2010 by Cospheric Microspheres Experts

A recent article on microspheres in Cosmetics & Toiletries magazine describes the use Solid Polyethylene Mirospheres for Effects in Color Cosmetics. Microspheres have been used in cosmetics for some time, primarily as fillers and exfoliators. Most recently scientists started to utilize light reflecting properties of microspheres for creating unique optical effects, such as optical blurring … Read more

Cosmetic Applications of Injectable Polymer Microspheres

January 3, 2021April 16, 2010 by Cospheric Microspheres Experts

Polymer microspheres, in particular injectable polymer particles with a diameter in the range of 30-300um, are becoming widely used as a biomaterial in different clinical fields, such as cosmetic surgery, reconstructive surgery, and urology. Injectable skin fillers offer many benefits in cosmetic dermatology, allowing new forms of facial rejuvenation and wrinkle treatment without surgery. Injectable … Read more

Motivations for Using Biodegradable Microspheres in Drug Delivery

January 3, 2021March 25, 2010 by Cospheric Microspheres Experts

In recent years there is significant interest in using biodegradable polymeric microspheres for drug delivery. Delivering drugs through biodegradable microspheres has numerous advantages compared to conventional delivery systems. While in conventional systems the drug is usually released shortly after delivery and stops working after a brief period of time, biodegradable polymer offers a way to provide sustained release over a longer time, thus eliminating the need for multiple doses and ensuring sustained and controlled drug delivery over weeks or months.

Porous Ceramics: Application for Polyethylene Microspheres

September 10, 2012March 13, 2010 by Cospheric Microspheres Experts

Background:

Usually porous ceramics are made from aluminum oxide, silicon carbide or Zirconia.? Most porous ceramics have a natural ability to fill pores by capillary action. This makes porous ceramics water accepting, thus they also are referred to as hydrophilic material. This means the pores and channels of a ceramic have a highly charged pore surface that attracts and bonds the polar molecules of water and other polar fluids. The net effect is called “wicking” — the ability to pull fluids into the material and transport that fluid by capillary forces.? The pore size directly affects the ceramic’s air entry or bubbling pressure and hydraulic conductivity. The effective pore size is determined by the minimum orifice within a channel or pore.¹

Some porous ceramic have 40-50% open porosity with a tortuous pore structure and is available in pore sizes ranging from 0.25 to 90 microns. Monolithic, single grade, aluminum oxide porous ceramic is available in 6, 15, 30, 50, 60 and 90 micron pore sizes. In addition, some ceramic membranes can use a medium pore substrate with a thin coating of fine porous ceramic membrane in 0.25, 1, 3 and 6 micron pore sizes.²

Dual nanocomposite multihollow polymer microspheres prepared by suspension polymerization based on a multiple pickering emulsion

September 17, 2014March 10, 2010 by Cospheric Microspheres Experts

Excerpts from an interesting approach to creating hollow polymer microspheres from a pickering emulsion.

Abstract:

A solid-stabilized multiple w/o/w or o/w/o emulsion was prepared in a two-step process. Various nanocomposite polymer microspheres with multihollow armored closed pores were fabricated easily by suspension polymerization of the multiple Pickering stabilized emulsions.

Read more

Measurement Techniques for Electrostatic Charged Microspheres

September 10, 2012March 10, 2010 by Cospheric Microspheres Experts

Charged Microspheres Measurement Techniques

Electrostatic charge (also known as triboelectric charge) on microparticles and microspheres have been of interest to scientists in chemical, pharmaceutical, cosmetic, drug delivery, displays and other industries for many years. Until recently there were no reliable techniques to measure or quantify electrostatic charge on microparticles, with too many uncontrolled variables the measurements were inconsistent. As a result scientists were treating charging as a black box process, performing the experiments blindly as trial and error. With recent advances in microsphere manufacturing, techniques have been developed that promise not only to quantify the charge on microspheres, but control it in the manufacturing process.

Electrostatic-based DNA Microarray Offers Medical Diagnostics Capabilities

September 10, 2012March 8, 2010 by Cospheric Microspheres Experts

The uses for microspheres continue to grow, a recent article published by UC-Berkley shows how DNA sequencing can be achieved through the use of statically charged microspheres. ? The key breakthrough is that they have been able to achieve a visible result through using the electrostatic repulsion of the microspheres. ? A copy of their announcement follows:

Groves,? and members of his research group Nathan Clack and Khalid Salaita, have published a paper on their technique in the journal Nature Biotechnology, which is now available online. The paper is entitled “Electrostatic readout of DNA microarrays with charged microspheres.“

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