Microspheres Online

Everything about microspheres and research utilizing precision spherical particles.

Custom Janus Particles, Microspheres, Microbeads – Bichromal Particles

Custom Janus Particles - Ceramic

What are Custom Janus Particles? Janus particle is anisotropic and refers to a particle, typically of spherical shape, with two hemispheres which may vary in color, optical properties, surface tension, electrostatic charge, magnetic response, conductivity, fluorescence, reflectivity and more. Custom Janus Particles Manufacturing Cospheric LLC uses a patented process to offer a unique capability of … Read more

Negatively-charged Yellow Microparticles – Back in Stock

Cospheric’s neutrally-buoyant highly charged yellow microspheres have a strong negative charge and are used by scientists in medical technology, biotechnology, applied physics and research. Precise particles with known density of 1.0g/cc that behave in a known way are useful as a model particles in simulation experiments.? Particles in a range of diameters from 5micron to … Read more

PIV Seeding – Microparticle Recommendations

Flow Visualization can best be accomplished with colored or fluorescent tracing particles of the same density as the fluid being studied. Very bright fluorescent micro-particles are available in densities of 1g/cc these offer not only bright testing under daylight conditions, but also the option of illumination with lasers or uv lights for increased system contrast.

Silane and Fluorochemical Coated Glass Spheres

The following products are offered in both Silane and Fluorochemical Coating.
P2011SL 3-6um mean diameter solid soda lime glass
P2015SL 8-12um mean diameter solid soda lime glass
P2050SL 35-45um mean diameter solid soda lime glass
P2075SL 65-75um mean diameter solid soda lime glass
P2453BTA 40-60um mean diameter solid barium titanate glass with aluminum shell.

Density Marker Beads

Materials of Microspheres

Density marker beads offer enable excellent stratification, and bright coloration for high visibility with the unaided eye. Density marker beads of accurately known mass density are generally used as an external marker to facilitate the monitoring of the density gradient shape and range. Historically density calibration beads in the size ranges of 212-250um or 250-300um are used.

Calculating microspheres per gram

During scientific experiment design and analysis it is common to need to know the number of spheres per gram of dry material. We have put together the table below to help speed up the process.

Monodisperse Silica Nanospheres and Microspheres – Dry Powder

Silica nanoparticles and nanospheres are now available in distributions of less than 10% CV in the sizes of 0.25 micron, 0.5micron, 0.75 micron, 1.0 micron, 4 micron and 8 micron.

Microbeads for Fish Egg Simulation: Dispersion and Recruitment

Microbeads for Fish Egg Simulaton

Scientists who study fish require artificial micro-particles to simulate fish eggs and their behavior in water. In order to accurately simulate the fish eggs it is important to use particles of the proper size and buoyancy/density. Particles with accurate size ranges and densities are now available.

Microspheres as Bond Line Spacers in Epoxies

Microspheres as Bond Line Spacer

Spacer Grade Glass Microspheres are presently used in gas plasma displays, automotive mirrors, electronic displays, flip chip technology, filters, sporting goods equipment, calibration standards and transformer manufacturing. Every day engineers are finding new and innovative uses for bond line spacers.

BioCompatability of Metal Coated Spheres

For those scientists?who are looking to use silver coated materials?such as silver coated microspheres in biomedical applications, it is important to understand whether they are bio-compatable.? A selection of abstracts and article references related to the biocompatability of silver follow:

The Biocompatibility of Silver2

The experiments reported have referred to some of the characteristics of the biocompatibility of Ag. Silver has been shown to display interactions with albumin, as an example of a plasma protein, quite different from those of most metals. Such studies shed further light on the complex issue of protein adsorption on biomaterials. It has also been demonstrated that Ag at concentrations < 1 ppm exerts a considerable influence on the activity of lactate dehydrogenase, this effect being reversed in the presence of albumin. A significant but transient increase in blood levels of Ag following intramuscular implantation of the metal has been observed. This is not reflected in any raised urine level. It is proposed that the richly vascular tissue immediately surrounding the implant in the acute phase of the response gives rise to the transient increase, but a subsequent decrease in vascularity reduces this possibility. It appears that Ag released from implants following this initial period substantially remains in the local area.2

Lack of toxicologocial side-effects in silver-coated megaprostheses in humans1

Deep infection of megaprostheses remains a serious complication in orthopedic tumor surgery. Furthermore, reinfection gets a raising problem in revision surgery of patients suffering from infections associated with primary endoprosthetic replacement of the knee and hip joint. These patients will need many revision surgeries and in some cases even an amputation is inevitable. Silver-coated medical devices proved their effectiveness on reducing infections, but toxic side-effects concerning some silver applications have been described as well. Our study reports about a silver-coated megaprosthesis for the first time and can exclude side-effects of silver-coated orthopedic implants in humans. The silver-levels in the blood did not exceed 56.4 parts per billion (ppb) and can be considered as non-toxic. Additionally we could exclude significant changes in liver and kidney functions measured by laboratory values. Histopathologic examination of the periprosthetic environment in two patients showed no signs of foreign body granulomas or chronic inflammation, despite distant effective silver concentrations up to 1626 ppb directly related to the prosthetic surface. In conclusion the silver-coated megaprosthesis allowed a release of silver without showing any local or systemic side-effects.1

Specific Article?References for the biocompatability of silver are below:

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